TH287
- TH287,TH-287
货号： abs810330
| 货号-规格 | 货期 | 价格 | 数量 |
| abs810330-5mg | 1-2周 | ￥830.00 | - + |
| abs810330-10mg | 1-2周 | ￥1138.00 | - + |
| abs810330-50mg | 1-2周 | ￥4542.00 | - + |
| abs810330-100mg | 1-2周 | ￥7883.00 | - + |
大包装询价| 产品描述 | ||
| 描述 | TH 287 is a first-in-class MTH1 inhibitor (IC50 value 5.0 nM) that selectively and effectively kills U2OS and other cancer cell lines, with considerably less toxicity towards several primary or immortalized cells. | |
| 纯度 | >98% | |
| 储存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. | |
| 基本信息 | ||
| 别名 | TH287,TH-287 | |
| 外观 | Powder | |
| 可溶性/溶解性 | DMSO 53 mg/mL (196.93 mM) Ethanol 10 mg/mL warmed (37.15 mM) | |
| 生物活性 | ||
| 靶点 | MTH1 | |
| In vitro(体外研究) | TH287 selectively and effectively kill U2OS and other cancer cell lines with less toxic to several primary or immortalized cells, and induces oxidative DNA damage. | |
| In vivo(体内研究) | In C57Bl/6 mice, TH287 (5 mk/kg, i.p.) causes a peak time and maximum concentration of 0.5 h and 0.82μM. | |
| 温馨提示：本产品仅作科研实验使用，不支持临床等研究 |
- 实验方法 实验条件
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Certificate of Analysis(COA)
