- 西维来司钠四水合物;EI546 sodium tetrahydrate;LY544349 sodium tetrahydrate; ONO5046 sodium tetrahydrate
货号: abs816085
货号-规格 | 货期 | 价格 | 数量 |
abs816085-10mg | 1-2周 | ¥772.00 | - + |
abs816085-50mg | 1-2周 | ¥2646.00 | - + |
abs816085-100mg | 1-2周 | ¥3859.00 | - + |
abs816085-200mg | 1-2周 | ¥6174.00 | - + |

产品描述 | ||
描述 | Sivelestat sodium is a competitive inhibitor of human neutrophil elastase, also inhibits leukocyte elastase obtained from rabbit, rat, hamster and mouse. | |
纯度 | >98% | |
储存/保存方法 | store at -20℃ for one year(Powder);
in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months. | |
基本信息 | ||
别名 | 西维来司钠四水合物;EI546 sodium tetrahydrate;LY544349 sodium tetrahydrate; ONO5046 sodium tetrahydrate | |
外观 | 白色粉末 | |
可溶性/溶解性 | DMSO :100mg/mL(189.21mM) Ethanol :100mg/mL(189.21mM) | |
生物活性 | ||
靶点 | neutrophil elastase | |
In vitro(体外研究) | Sivelestat suppresses both adhesion and transmigration of neutrophils to the endothelium. | |
In vivo(体内研究) | Intraoperative administration of sivelestat effectively reduced neutrophil induction and activation in the lung and improved oxygenation after cardiopulmonary bypass in a piglet model.By inhibiting neutrophil elastase, sivelestat has a direct action to the accumulated and activated leucocytes, offering efficient protection against theproduction of oxygen radicals and cytokines. | |
参考文献 | ||
参考文献 | ||
温馨提示:本产品仅作科研实验使用,不支持临床等研究 |
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