- 西维来司钠四水合物；EI546 sodium tetrahydrate；LY544349 sodium tetrahydrate； ONO5046 sodium tetrahydrate
货号： abs816085
| 货号-规格 | 货期 | 价格 | 数量 |
| abs816085-10mg | 1-2周 | ￥772.00 | - + |
| abs816085-50mg | 1-2周 | ￥2646.00 | - + |
| abs816085-100mg | 1-2周 | ￥3859.00 | - + |
| abs816085-200mg | 1-2周 | ￥6174.00 | - + |
大包装询价| 产品描述 | ||
| 描述 | Sivelestat sodium is a competitive inhibitor of human neutrophil elastase, also inhibits leukocyte elastase obtained from rabbit, rat, hamster and mouse. | |
| 纯度 | ＞98% | |
| 储存/保存方法 | store at -20℃ for one year（Powder）；
in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months. | |
| 基本信息 | ||
| 别名 | 西维来司钠四水合物；EI546 sodium tetrahydrate；LY544349 sodium tetrahydrate； ONO5046 sodium tetrahydrate | |
| 外观 | 白色粉末 | |
| 可溶性/溶解性 | DMSO ：100mg/mL(189.21mM) Ethanol ：100mg/mL(189.21mM) | |
| 生物活性 | ||
| 靶点 | neutrophil elastase | |
| In vitro(体外研究) | Sivelestat suppresses both adhesion and transmigration of neutrophils to the endothelium. | |
| In vivo(体内研究) | Intraoperative administration of sivelestat effectively reduced neutrophil induction and activation in the lung and improved oxygenation after cardiopulmonary bypass in a piglet model.By inhibiting neutrophil elastase, sivelestat has a direct action to the accumulated and activated leucocytes, offering efficient protection against theproduction of oxygen radicals and cytokines. | |
| 参考文献 | ||
| 参考文献 | ||
| 温馨提示：本产品仅作科研实验使用，不支持临床等研究 |
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Certificate of Analysis(COA)
