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Fig. 2. Adoptive transfer of antigen-specific Tregs promotes Th17 cell generation in EAE. C57BL/6 mice were subcutaneously injected with MOG35-55 peptide emulsified in complete Freund's adjuvant (CFA) to induce EAE, and MOG-specific Tregs were injected intravenously into mice of the Treg cell therapy group on day 9. (A) EAE clinical scores of indicated groups. (B) Representative histology images of spinal cord sections. Scale bars, 400μm. (C) Total Immune cell numbers in the spleen, DLN, brain and spinal cord tissues of indicated mice.
来源于《Nat Commun》
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