Metyrapone
- 美替拉酮；甲吡酮；Su-4885
货号： abs816604
| 货号-规格 | 货期 | 价格 | 数量 |
| abs816604-50mg | 1-2周 | ￥353.00 | - + |
| abs816604-100mg | 1-2周 | ￥497.00 | - + |
| abs816604-200mg | 1-2周 | ￥557.00 | - + |
| abs816604-500mg | 1-2周 | ￥607.00 | - + |
大包装询价| 产品描述 | ||
| 描述 | An inhibitor of the enzyme steroid 11-beta-monooxygenase. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of cushing syndrome. | |
| 纯度 | 98% | |
| 储存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. | |
| 基本信息 | ||
| 别名 | 美替拉酮；甲吡酮；Su-4885 | |
| 可溶性/溶解性 | water : ≥ 38 mg/mL (167.94 mM) | |
| 生物活性 | ||
| 靶点 | 11β-HSD1 | |
| In vitro(体外研究) | Metyrapone is a well known inhibitor of 11β-hydroxylase, a key enzyme involved in the final step of cortisol biosynthesis. At higher concentrations, it also inhibits other steroidogenic enzymes such as cholesterol side chain cleavage enzyme. It is specific for 11β-HSD1 while it has little effect on 11β-HSD2 activity. | |
| In vivo(体内研究) | The administration of metyrapone to man, and animals such as the dog and sheep thus leads to a decrease in circulating levels of cortisol. | |
| 参考文献 | ||
| 参考文献 | ||
| 温馨提示：本产品仅作科研实验使用，不支持临床等研究 |
- 实验方法 实验条件
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