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  • Beta-Amyloid (1-28)
  • 货号: abs45151803
    分子量: 3262.5
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    货号-规格 货期 价格 数量
    abs45151803-0.5mg 4周 ¥1470.00
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    产品描述
    描述

    The three-dimensional solution structure of Aß (1-28) reveals the folding of the peptide to form a predominantly a-helical structure with a bend centered at residue 12 and the side chains of histidine-13 and lysine-16 in close proximity, residing on the same face of the helix. Their proximity may constitute a binding motif with the heparan sulfate proteoglycans. Aß (1-28) is highly hydrophilic and shares sequences with bA4, the major component of Aß. Its assembly is fibrillar, i.e., elongated in a single direction. Reports show that synthetic peptides Aß (1-40) and Aß (1-28) have significant effects on normal human plasma cholesterol esterification rate. Both peptides (at concentration of 1 ng/mL) inhibit plasma cholesterol esterification rate by 40-50% compared to the control value.

    纯度
    ≥ 95%
    储存/保存方法
    -20°C
    参考文献
    参考文献
    Kirshenbaum K. and V. Daggett, Biochem. 34, 7640 (1995); Talafous, J. et al. Biochem. 33, 7788 (1994).
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