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  • Alizapride hydrochloride
    • 盐酸阿立必利
    货号: abs813468
    CAS号: 59338-87-3
    分子式: C16H21N5O2.HCl
    分子量: 351.83
    产品说明书
    分享:
    货号-规格 货期 价格 数量
    abs813468-25mg 1-2周 ¥524.00
    - +
    abs813468-50mg 1-2周 ¥834.00
    - +
    abs813468-100mg 1-2周 ¥1489.00
    - +
    大包装询价
    产品描述
    描述

    Alizapride hydrochloride is a dopamine receptor antagonist used for the theropy of nausea and vomiting.

    纯度
    >98%
    储存/保存方法
    store at -20℃ for one year(Powder);
    in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months.
    基本信息
    别名
    盐酸阿立必利
    可溶性/溶解性
    DMSO :39 mg/mL (110.8 mM)

    Water :64 mg/mL (181.9 mM)
    生物活性
    靶点
    Dopamine receptor
    In vitro(体外研究)
    Alizapride has a N-allyl moiety which potentially could undergo N-deallylation and/or epoxidation reactions, the formation of chemically reactive metabolites can be expected.
    In vivo(体内研究)
    Alizapride demonstrates little toxicity (particularly after parenteral administration) in mice and rats. Alizapride is mainly excreted as unmodified drug after oral or parenteral administration; however, a share of about 25% undergoes metabolic transformation before deletion. Alizapride (5 mg/kg, s.c.) antagonizes the decrease in gastrointestinal transit induced by the above doses of Apomorphine in the rat.
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