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  • Aciclovir

    • 阿昔洛韦;Aciclovir; Acycloguanosine
    货号: abs817232
    CAS号: 59277-89-3
    分子式: C8H11N5O3
    分子量: 225.21
    产品说明书
    分享:
    货号-规格 货期 价格 数量
    abs817232-25mg 1-2周 ¥549.00
    - +
    abs817232-50mg 1-2周 ¥604.00
    - +
    abs817232-100mg 1-2周 ¥944.00
    - +
    abs817232-200mg 1-2周 ¥1227.00
    - +
    大包装询价
    产品描述
    描述

    Acyclovir is a synthetic nucleoside analogue active against herpesviruses. It is a guanosine analogue antiviral drug. Aciclovir differs from previous nucleoside analogues in that it contains only a partial nucleoside structure: the sugar ring is replaced by an open-chain structure.

    纯度
    >98%
    储存/保存方法
    Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
    基本信息
    别名
    阿昔洛韦;Aciclovir; Acycloguanosine
    外观
    白色结晶性粉末
    可溶性/溶解性
    DMSO:45 mg/mL (199.82 mM)
    生物活性
    靶点
    DNA synthesis
    In vitro(体外研究)
    Acyclovir sensitivity of herpes simplex virus isolates is determined in a plaque-reduction assay in Vero cells. IC50 Values are consistently 2-3 fold lower in B2 compared with the H strain of Vero cells. HSV Type 2 strains are 2-10-fold less sensitive than Type 1 strains.
    In vivo(体内研究)

    low-dose oral acyclovir may be effective in the prevention of HSV infection during OKT3 treatment of seropositive patients. Continuation of acyclovir prophylaxis for two to four weeks following the conclusion of OKT3 therapy may prevent occurrence of delayed infections.
    参考文献
    参考文献
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