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  • Abarelix Acetate

    • 阿巴瑞克;R3827;PPI 149
    货号: abs815849
    CAS号: 183552-38-7
    分子式: C72H95ClN14O14
    分子量: 1416.1
    产品说明书
    分享:
    货号-规格 货期 价格 数量
    abs815849-5mg 1-2周 ¥1544.00
    - +
    abs815849-10mg 1-2周 ¥2536.00
    - +
    abs815849-25mg 1-2周 ¥5733.00
    - +
    abs815849-50mg 1-2周 ¥9923.00
    - +
    大包装询价
    产品描述
    描述

    Abarelix is a potent gonadotrophin-releasing hormone (GnRH) antagonist, used for prostate cancer treatment..

    序列
    Ac-D2Nal-DCpa-DPal-Ser-NMeTyr-DAsp-Leu-Lys(ipr)-Pro-DAla-NH2
    纯度
    98%
    储存/保存方法
    Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
    基本信息
    别名
    阿巴瑞克;R3827;PPI 149
    外观
    White powder
    可溶性/溶解性
    DMSO : ≥ 14.2 mg/mL (10.03 mM)
    生物活性
    靶点
    GNRH Receptor
    In vitro(体外研究)
    Abarelix (30 and 300 µg/mL) and cetrorelix cause significantly increased histamine release. Abarelix is the firstGnRH antagonist to be developed, and can produce rapid and sustained decreases in testosterone to castrate levels without the need for co-administration of an antiandrogen, and with a very low complication rate in the short term. Abarelix demonstrates to promptly and substantially reduce follicle-stimulating hormone levels to lower than LHRH agonist. Abarelix does not cause a surge in serum testosterone that can precipitate a flare phenomenon or worsening of disease, particularly dangerous for patients with metastatic, symptomatic disease, and produces medical castration more quickly.
    温馨提示:本产品仅作科研实验使用,不支持临床等研究
    • 实验方法 实验条件
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