A-1331852
- A 1331852;A1331852
货号: abs814225
货号-规格 | 货期 | 价格 | 数量 |
abs814225-5mg | 1-2周 | ¥1379.00 | - + |
abs814225-10mg | 1-2周 | ¥2315.00 | - + |
abs814225-25mg | 1-2周 | ¥4410.00 | - + |
abs814225-50mg | 1-2周 | ¥7828.00 | - + |

产品描述 | ||
描述 | A-1331852 is a high affinity BH3 mimetic Ligand of BCL protein BCL-XL. | |
纯度 | >98% | |
储存/保存方法 | Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution. | |
基本信息 | ||
别名 | A 1331852;A1331852 | |
外观 | Powder | |
可溶性/溶解性 | DMSO : ≥ 50 mg/mL (75.89 mM) | |
生物活性 | ||
靶点 | Bcl-xL | |
In vitro(体外研究) | A-1331852 exhibits remarkable potency both as a single agent and in combination with TKIs in killing primary CD34+ CML cell. Also, It has remarkable potency in inducing apoptosis in these cells at lownanomolar concentrations as early as 1 h post-treatment. | |
In vivo(体内研究) | A-1331852 demonstrates antitumor efficacy in the Molt-4 xenograft model, inducing tumor regressions as a single agent. | |
温馨提示:本产品仅作科研实验使用,不支持临床等研究 |
- 实验方法 实验条件
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