货号： abs818316
| 货号-规格 | 货期 | 价格 | 数量 |
| abs818316-1mg | 1-2周 | ￥1940.00 | - + |
| abs818316-5mg | 1-2周 | ￥5821.00 | - + |
大包装询价| 产品描述 | ||
| 描述 | 4E2RCat is an inhibitor of eIF4E-eIF4G interaction with an IC50 of 13.5 μM. | |
| 基本信息 | ||
| 可溶性/溶解性 | DMSO: 15.5 mg/mL | |
| 生物活性 | ||
| 靶点 | Eukaryotic Initiation Factor (eIF) | |
| In vitro(体外研究) | 4E2RCat prevents the interaction between eIF4E (the cap-binding protein) and eIF4G (a large scaffolding protein), inhibiting cap-dependent translation. It significantly decreases human coronavirus 229E (HCoV-229E) replication, reducing the percentage of infected cells and intra- and extracellular infectious virus titers. 4E2RCat inhibits cap-dependent translation in a dose-dependent manner. 4E2RCat inhibits cap-dependent FF translation but not EMCV IRES-driven Ren translation. 4E2RCat inhibits coronavirus replication in a dose- and time-dependent manner. | |
| In vivo(体内研究) | 4E2RCat inhibits protein synthesis in vivo and it is not a consequence of increased cell death. | |
| 参考文献 | ||
| 参考文献 | ||
| 温馨提示：本产品仅作科研实验使用，不支持临床等研究 |
- 提示： 尊敬的客户您好，如果您对我们的产品有什么疑问或想要了解的，可以点击“我要提问”按钮填写您的疑问。
提交不成功？请联系info@absin.cn。
Certificate of Analysis(COA)
