β-淀粉样多肽(1-42)
- Β淀粉样肽-42 (C端多肽); BETA-淀粉样蛋白-42,Amyloid b-Protein (1-42)
货号: abs45128173
货号-规格 | 货期 | 价格 | 数量 |
abs45128173-1mg | 现货 | ¥2822.00 | - + |
abs45128173-5mg | 现货 | ¥3528.00 | - + |
abs45128173-10mg | 4周 | ¥5544.00 | - + |

产品描述 | |
描述 | Aβ 1-42, 42-residue fragment of amyloid precursor protein, has been found to be a major constituent of the senile plaques formed in the brains of patients with Alzheimer´s disease and late Down´s syndrome. Aβ 1-42 readily forms neurotoxic oligomers at physiological pH. On the other hand, the peptide shows antimicrobial activity. The sequence of H-1368 corresponds to the human, bovine, canine, feline, ovine, guinea pig, and rabbit Aβ42 peptide. The peptide has been used to detect amyloid β-protein multimers in the cerebrospinal fluid of Alzheimer´s disease patients through fluorescence correlation spectroscopy. For detailed descriptions of the preparation of Aβ 1-42 monomers and protofibrils please see the papers of Jan, Hartley, and Lashuel, Stine et al. (2011), and of Broersen and colleagues. The findings of Ryan et al. indicate that 10% ammonia disaggregates Aβ42 more efficiently than HFIP. |
来源 | 合成 |
序列 | H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH |
纯度 | 95% |
储存/保存方法 | -20 °C,避光,干燥,有效期1年。 |
基本信息 | |
别名 | Β淀粉样肽-42 (C端多肽); BETA-淀粉样蛋白-42 |
外观 | white Lyophilized powder |
温馨提示:本产品仅作科研实验使用,不支持临床等研究 |
- 实验方法 实验条件
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