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  • Ammonium Glycyrrhizinate
  • 甘草酸单铵盐;AMGZ;Glycyram
  • 货号: abs816403
    CAS号: 1407-03-0
    分子式: C42H62O16.NH3
    分子量: 839.96
    产品说明书
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    货号-规格 货期 价格 数量
    abs816403-5mg 1-2周 ¥536.00
    - +
    abs816403-10mg 1-2周 ¥961.00
    - +
    abs816403-25mg 1-2周 ¥1740.00
    - +
    abs816403-50mg 1-2周 ¥2670.00
    - +
    大包装询价
    产品描述
    描述

    Mono-ammonium glycyrrhizinate (AMGZ) is a unique product derived from Licorice root and has an extremely sweet taste. It is an excellent foaming agent that acts as a co-emulsifier. It is also excellent in recipes that require gelling or suspension properties for a consistent feeling in the mouth or a stable cloud effect in the product.Very small quantities are required to achieve the desired results, usually a few parts per million. However, varying amounts should be evaluated in your product for best taste.MAGZ is up to 50 times sweeter than sucrose — and can greatly enhance an already sweetened product as a result of synergies with both natural and synthetic sweeteners. It was found to be active against viruses, while not affecting cell activity and ability to replicate. It was also reported that glycyrrhizic acid inactivates herpes simplex particles irreversibly.

    纯度
    >98%
    储存/保存方法
    store at -20℃ for one year(Powder);
    in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months.
    基本信息
    别名
    甘草酸单铵盐;AMGZ;Glycyram
    外观
    白色或淡黄色粉末
    可溶性/溶解性
    DMSO :155 mg/mL (184.5 mM)

    Water :5 mg/mL (5.95 mM)
    生物活性
    靶点
    11-beta-hydroxysteroid dehydrogenases
    In vitro(体外研究)
    Ammonium glycyrrhizinate (AG) prepared from glycyrrhizin dramatically protects AGS cells from H(2)O(2)-induced damage as measured by the integrity of actin cytoskeleton. AG also inhibits FeSO(4)-induced reactive oxygen radicals in a dose-dependent manner, suggesting the role for AG as a free radical scavenger.
    In vivo(体内研究)
    Ammonium glycyrrhizinate (28 mg/kg) leads to changes in the activity of some enzymes in the brain, the development of parenchymatous dystrophy of the liver which changed to acidophilic necrosis attended with signs of regeneration in mice and rats model. Ammonium glycyrrhizinate-loaded nonionic surfactant vesicles (NSVs) decreases edema and nociceptive responses when compared with Ammonium glycyrrhizinate alone and empty NSVs in mice model. Ammonium glycyrrhizinate up-regulates interleukin-10 (IL-10) level and down-regulates the tumor neurosis factor-α (TNF-α) level and inhibits the cyclic adenosine monophosphate-phosphodiesterase (cAMP-PDE) activity in the lung tissue of mice. Ammonium glycyrrhizinate -loaded non-ionic surfactant vesicles shows no toxicity, good skin tolerability and are able to improve the drug anti-inflammatory activity in mice. Ammonium glycyrrhizinate significantly decreases triglyceride, cholesterol, low density lipoprotein (LDL) and very low density lipoprotein (VLDL) levels in rats. Ammonium glycyrrhizinate increases high density lipoprotein (HDL) levels increased in rats.
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