Sograzepide
- Netazepide；YF 476；YM-220
货号： abs820922
| 货号-规格 | 货期 | 价格 | 数量 |
| abs820922-5mg | 1-2周 | ￥4631.00 | - + |
| abs820922-50mg | 1-2周 | ￥21830.00 | - + |
大包装询价| 产品描述 | ||
| 描述 | Sograzepide (Netazepide;YF476) is a gastrin/cholecystokinin 2 receptor (CCK2) antagonist. | |
| 纯度 | 98% | |
| 储存/保存方法 | Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution. | |
| 基本信息 | ||
| 别名 | Netazepide；YF 476；YM-220 | |
| 可溶性/溶解性 | DMSO : ≥ 100 mg/mL (200.57 mM) | |
| 生物活性 | ||
| 靶点 | Gastrin/cholecystokinin 2 receptor (CCK2) | |
| In vivo(体内研究) | Sograzepide (Netazepide; YF 476; YM-220) (0.1 μmol/kg; intravenous injection) has an inhibition effect on pentagastrin-induced gastric acid secretion in anethsetized rats with an ED50 of 87 nmol/kg. Sograzepide (Netazepide; YF 476; YM-220) (intravenous injection; 10 μM/kg) inhibits pentagastrin-induced acid secretion with an ED50 value of 0.0086 μM/kg, but does not affect histamine- and bethanechol-induced acid secretion. Sograzepide (Netazepide; YF 476; YM-220) (intravenous injection; oral administration) in Heidenhain pouch dogs, inhibits pentagastrin-stimulated gastric acid secretion in a dose-dependent manner with ED50 values of 0.018 and 0.020 μM/kg, respectively. | |
| 温馨提示：本产品仅作科研实验使用，不支持临床等研究 |
- 实验方法 实验条件
共 0张，还能上传 8张 提交
- 提示： 尊敬的客户您好，如果您对我们的产品有什么疑问或想要了解的，可以点击“我要提问”按钮填写您的疑问。
提交不成功？请联系info@absin.cn。
Certificate of Analysis(COA)
