Sograzepide
- Netazepide;YF 476;YM-220
货号: abs820922
货号-规格 | 货期 | 价格 | 数量 |
abs820922-5mg | 1-2周 | ¥4631.00 | - + |
abs820922-50mg | 1-2周 | ¥21830.00 | - + |

产品描述 | ||
描述 | Sograzepide (Netazepide;YF476) is a gastrin/cholecystokinin 2 receptor (CCK2) antagonist. | |
纯度 | 98% | |
储存/保存方法 | Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution. | |
基本信息 | ||
别名 | Netazepide;YF 476;YM-220 | |
可溶性/溶解性 | DMSO : ≥ 100 mg/mL (200.57 mM) | |
生物活性 | ||
靶点 | Gastrin/cholecystokinin 2 receptor (CCK2) | |
In vivo(体内研究) | Sograzepide (Netazepide; YF 476; YM-220) (0.1 μmol/kg; intravenous injection) has an inhibition effect on pentagastrin-induced gastric acid secretion in anethsetized rats with an ED50 of 87 nmol/kg. Sograzepide (Netazepide; YF 476; YM-220) (intravenous injection; 10 μM/kg) inhibits pentagastrin-induced acid secretion with an ED50 value of 0.0086 μM/kg, but does not affect histamine- and bethanechol-induced acid secretion. Sograzepide (Netazepide; YF 476; YM-220) (intravenous injection; oral administration) in Heidenhain pouch dogs, inhibits pentagastrin-stimulated gastric acid secretion in a dose-dependent manner with ED50 values of 0.018 and 0.020 μM/kg, respectively. | |
温馨提示:本产品仅作科研实验使用,不支持临床等研究 |
- 实验方法 实验条件
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