Recombinant SARS-CoV-2 Nucleocapsid NTD Protein N-8His

SARS-CoV-2 coronavirus NP Protein; SARS-CoV-2 np Protein; SARS-CoV-2 novel coronavirus Nucleoprotein Protein

SARS-CoV-2

E.coli

15.2 kDa (Reducing)

Lyophilized Powder

Lyophilized from a 0.22 μm filtered solution of 20mM PB, 100mM NaCl, pH7.4.

Asn48-Glu174

N-8His

＞98% by SDS-PAGE&RP-HPLC

＜1 EU/μg(LAL)

unconjugated

Centrifuge tubes before opening.Reconstitute no more than 1 mg/mL according to the size in deionized water.

Within 1 month, 2 to 8 °C under sterile conditions after reconstitution. 12 months from date of receipt, -20 to -80 °C as supplied. Avoid repeated freeze-thaw cycles.

Nucleocapsid, nucleocapsid protein, is an important structural protein of the new coronavirus SARS-CoV-2, responsible for wrapping the viral RNA genome and then assembling into virus particles. Nucleocapsid has two domains: NTD and CTD. The surface of NTD protein has multiple positively charged arginine residues, which can combine with negatively charged RNA genome in a charge interaction manner to form a nucleocapsid complex. important role in virus replication. Therefore, in the development of new coronavirus SARS-CoV-2 therapeutic drugs, NTD inhibitors have become popular targets for drug screening. At the same time, the antigen detection kit developed for NTD provides a more efficient and accurate detection method for SARS-CoV-2 detection. This product is made from the N-terminal domain NTD protein of the Nucleocapsid of the new coronavirus SARS-CoV-2 recombinantly expressed in Escherichia coli, after multi-step purification and filter sterilization.

P0DTC9