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  • Recombinant Human SARS-CoV-2 Spike RBD (BA.4 /Omicron) Protein C-8His

    货号: abs05128
    产品说明书
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    货号-规格 货期 价格 数量
    abs05128-100ug 现货 ¥3600.00
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    大包装询价
    概述
    种属
    SARS-CoV-2
    来源
    HEK293
    分子量
    35-40 kDa(Reducing)
    外观
    Lyophilized Powder
    形态
    Lyophilized from a 0.22 μm filtered solution of PBS, pH7.4.
    性能
    序列
    Arg319-Phe541
    (The mutations included G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H)
    RVQPTESIVRFPNITNLCPFDEVFNATRFASVYAWNRKRISNCVADYSVLYNFAPFFAFKCYGVSPTKLNDLCFTNVYADSFVIRGNEVSQIAPGQTG
    标签
    C-8His
    纯度
    >95% SDS-PAGE&RP-HPLC
    内毒素水平
    <0.1EU/μg(LAL)
    溶解方法
    Centrifuge tubes before opening.Reconstitute no more than 1 mg/mL according to the size in deionized water.
    储存/保存方法
    Within 1 month, 2 to 8 °C under sterile conditions after reconstitution. 12 months from date of receipt, -20 to -80 °C as supplied. Avoid repeated freeze-thaw cycles.
    靶标
    背景说明
    Coronaviruses (CoVs) are enveloped viruses with a positive sense RNA genome, that belong to the subfamily Coronavirinae within the family Coronaviridae, which is part of the Nidovirales order. The CoV virion contains at least four structural proteins: spike (S), envelope (E), membrane (M) and nucleocapsid (N). Among them, the S protein plays an essential role in viral attachment, fusion, entry, and transmission. It comprises an N-terminal S1 subunit responsible for virus–receptor binding and a C-terminal S2 subunit responsible for virus–cell membrane fusion. S1 is further divided into an N-terminal domain (NTD) and a receptor-binding domain (RBD). During infection, CoV first binds the host cell through interaction between its S1-RBD and the cell membrane receptor, triggering conformational changes in the S2 subunit that result in virus fusion and entry into the target cell.
    Accession
    P0DTC2
    2μg(R: reducing conditions, N: non-reducing conditions).
    RP-HPLC
    温馨提示:本产品仅作科研实验使用,不支持临床等研究
    • 实验方法 实验条件
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