Recombinant Human SARS-CoV-2 Spike RBD (BA.4 /Omicron) Protein C-8His
货号: abs05128
货号-规格 | 货期 | 价格 | 数量 |
abs05128-100ug | 现货 | ¥3600.00 | - + |

概述 | ||
种属 | SARS-CoV-2 | |
来源 | HEK293 | |
分子量 | 35-40 kDa(Reducing) | |
外观 | Lyophilized Powder | |
形态 | Lyophilized from a 0.22 μm filtered solution of PBS, pH7.4. | |
性能 | ||
序列 | Arg319-Phe541 (The mutations included G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H) RVQPTESIVRFPNITNLCPFDEVFNATRFASVYAWNRKRISNCVADYSVLYNFAPFFAFKCYGVSPTKLNDLCFTNVYADSFVIRGNEVSQIAPGQTG | |
标签 | C-8His | |
纯度 | >95% SDS-PAGE&RP-HPLC | |
内毒素水平 | <0.1EU/μg(LAL) | |
溶解方法 | Centrifuge tubes before opening.Reconstitute no more than 1 mg/mL according to the size in deionized water. | |
储存/保存方法 | Within 1 month, 2 to 8 °C under sterile conditions after reconstitution. 12 months from date of receipt, -20 to -80 °C as supplied. Avoid repeated freeze-thaw cycles. | |
靶标 | ||
背景说明 | Coronaviruses (CoVs) are enveloped viruses with a positive sense RNA genome, that belong to the subfamily Coronavirinae within the family Coronaviridae, which is part of the Nidovirales order. The CoV virion contains at least four structural proteins: spike (S), envelope (E), membrane (M) and nucleocapsid (N). Among them, the S protein plays an essential role in viral attachment, fusion, entry, and transmission. It comprises an N-terminal S1 subunit responsible for virus–receptor binding and a C-terminal S2 subunit responsible for virus–cell membrane fusion. S1 is further divided into an N-terminal domain (NTD) and a receptor-binding domain (RBD). During infection, CoV first binds the host cell through interaction between its S1-RBD and the cell membrane receptor, triggering conformational changes in the S2 subunit that result in virus fusion and entry into the target cell. | |
Accession | P0DTC2 | |
2μg(R: reducing conditions, N: non-reducing conditions). | ||
RP-HPLC | ||
温馨提示:本产品仅作科研实验使用,不支持临床等研究 |
- 实验方法 实验条件
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