Recombinant Human PD-1 His Tag全线7折
- PD-1蛋白,Programmed cell death protein 1,hPD-1,PDCD1,CD279
PD-1蛋白;Programmed cell death protein 1,hPD-1,PDCD1,CD279
28-36 kDa (Reducing)
Lyophilized from a 0.22 μm filtered solution of PBS, 5% trehalose, pH 7.4.
＞95% by SDS-PAGE(Reducing)
＜0.1 EU/μg (gel-clot)
Centrifuge tubes before opening.Reconstitute no more than 1 mg/mL according to the size in deionized water.
Within 1 month, 2 to 8 °C under sterile conditions after reconstitution. 12 months from date of receipt, -20 to -80 °C as supplied. Avoid repeated freeze-thaw cycles.
This product contains 5% trehalose, if you need recombinant protein without added trehalose, please contact us.
PD-1 (programmed death 1) programmed death receptor 1 is an important immunosuppressive molecule, belonging to the immunoglobulin superfamily, and is a membrane protein of 268 amino acid residues. Immunomodulation targeting PD-1 is of great significance in anti-tumor, anti-infection, anti-autoimmune diseases and organ transplantation survival. Its ligand PD-L1 can also be used as a target. The combination of PD-1 and PD-L1 initiates the programmed death of T cells and enables tumor cells to obtain immune escape. This product is made from HEK293 cell line expressing human PD-1, C-6His recombinant protein, after multi-step purification, filtering, adding 5% trehalose, and lyophilizing.
|1μg (NR: non-reducing conditions, R: reducing conditions).|
|Immobilized PD-1 His Tag, Human (Cat. No. abs05023) at 1.5μg/mL (100μL/well) can bind PD-L1 Fc Chimera, Human (Cat. No. abs05024) with an EC50 of 0.141-0.174µg/mL.|
|PD-1 His Tag, Human (Cat. No. abs05023) captured on CM5 chip via, can bind PD-L1 Fc Chimera, Human (Cat. No. abs05024) with an affinity constant of 0.6644 μM as determined in a SPR assay (Biacore T200).|
|Loaded PD-L1 Fc Chimera, Human (Cat. No. abs05024) on Protein A Biosensor, can bind PD-1 His Tag, Human (Cat. No. abs05023) with an affinity constant of 1.6 μM as determined in BLI assay.|
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