Recombinant Human PD-1 Fc Chimera

PD-1 Fc Chimera蛋白;Programmed cell death protein 1,hPD-1,PDCD1,CD279

Human

HEK293

55-65 KD (Reducing)

Lyophilized Powder

Lyophilized from a 0.22 μm filtered solution of PBS, 5% trehalose, pH 7.4.

Leu25-Gln167

C-Fc

＞95% by SDS-PAGE(Reducing)

＜0.1 EU/μg (gel-clot)

unconjugated

Centrifuge tubes before opening.Reconstitute no more than 1 mg/mL according to the size in deionized water.

Within 1 month, 2 to 8 °C under sterile conditions after reconstitution. 12 months from date of receipt, -20 to -80 °C as supplied. Avoid repeated freeze-thaw cycles.

This product contains 5% trehalose, if you need recombinant protein without added trehalose, please contact us.

PD-1 (programmed death 1) programmed death receptor 1 is an important immunosuppressive molecule, belonging to the immunoglobulin superfamily, and is a membrane protein of 268 amino acid residues. Immunomodulation targeting PD-1 is of great significance in anti-tumor, anti-infection, anti-autoimmune diseases and organ transplantation survival. Its ligand PD-L1 can also be used as a target. The combination of PD-1 and PD-L1 initiates the programmed death of T cells and enables tumor cells to obtain immune escape.This product is made from human PD-1 expressed by HEK293 cell line, fused with human IgG1 Fc recombinant protein, and after multi-step purification, sterile filtration, adding 5% trehalose, and freeze-drying.

Q15116