Recombinant Human IL-31 Protein

1ug (R: reducing condition, N: non-reducing condition).

Measured by its binding ability in a functional ELISA. When Recombinant Human IL-31 is immobilized 2.5µg/mL (100µL/well), Recombinant Human OSMR/IL-31RB His Tag binds with an EC50 of 1.3-1.6ug/mL.

Measured by its binding ability in a functional ELISA. When Recombinant Human IL-31 is immobilized 2.5µg/mL (100µL/well), Recombinant Mouse IL-31RA Fc chimera binds with an EC50 of 0.07-0.1ug/mL.

Measured by its ability to induce STAT3 activation in U‑87 MG human glioblastoma/astrocytoma cells. The EC50 for this effect is less than 30ng/mL can effectively induce STAT3 activation.