Rabbit anti-14-3-3 zeta Polyclonal Antibody

14-3-3 ζ抗体;14 3 3 delta, 14 3 3 protein zeta/delta, 14 3 3 protein/cytosolic phospholipase A2, 14 3 3 zeta, 14-3-3 protein zeta/delta, 1433Z_HUMAN, Epididymis luminal protein 4, Epididymis secretory protein Li 3, HEL S 3, HEL4, KCIP-1, KCIP1, MGC111427, MGC126532, MGC138156, Phospholipase A2, Protein kinase C inhibitor protein 1, Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, delta polypeptide, Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, zeta, Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, zeta polypeptide, Tyrosine 3/tryptophan 5 monooxygenase activation protein, zeta polypeptide, YWHAD, YWHAZ,

Rabbit

14-3-3 ζ Antibody detects endogenous levels of total 14-3-3 ζ.

Human;Mouse;Rat

WB 1:500~1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Predicted molecular weight: 28kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

A synthesized peptide derived from Human YWHAZ(Accession P63104), corresponding to amino acid residues L43-K68.

1mg/ml

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin .

Polyclonal Antibody

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.

The delta, brain-specific form differs from the zeta form in being phosphorylated (By similarity). Phosphorylation on Ser-184 by MAPK8; promotes dissociation of BAX and translocation of BAX to mitochondria. Phosphorylation on Thr-232; inhibits binding of RAF1. Phosphorylated on Ser-58 by PKA and protein kinase C delta type catalytic subunit in a sphingosine-dependent fashion. Phosphorylation on Ser-58 by PKA; disrupts homodimerization and heterodimerization with YHAE and TP53.

Cytosol;Extracellular region or secreted;Mitochondrion;Nucleus;