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  • Rabbit anti-ZC12A (Center) Polyclonal Antibody
  • Ribonuclease ZC3H12A, 31--, MCP-induced protein 1, Zinc finger CCCH domain-containing protein 12A, ZC3H12A {ECO:0000312|EMBL:EAX073461};ZC3H12A {ECO:0000312|EMBL:EAX07346.1}
  • 货号: abs100885
    产品说明书
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    货号-规格 货期 价格 数量
    abs100885-50ul 1-2周 ¥1250.00
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    大包装询价
    概述
    描述
    Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
    别名
    Ribonuclease ZC3H12A, 31--, MCP-induced protein 1, Zinc finger CCCH domain-containing protein 12A, ZC3H12A {ECO:0000312|EMBL:EAX073461};ZC3H12A {ECO:0000312|EMBL:EAX07346.1}
    宿主
    Rabbit
    特异性
    This ZC12A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-358 amino acids from the Central region of human ZC12A.
    反应种属
    Human
    应用
    WB~~1:1000
    IHC-P~~1:50~100
    FC~~1:10~50
    性能
    类型
    Polyclonal Antibody
    同种型
    Rabbit Ig
    储存/保存方法
    Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
    存储溶液
    Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
    研究领域
    Cancer;Cell Biology;Immunology
    靶标
    背景说明
    Has RNase activity and selectively degrades specific target mRNA species. Modulates the immune response and inflammation by regulating the decay of specific mRNA molecules. Recognizes the 3'-untranslated region (UTR) of the mRNA for IL6, CALCR and IL12B. Required for normal decay of IL6 mRNA (By similarity). Triggers apoptosis and promotes angiogenesis in response to the binding of CCL2 to CCR2. Regulates expression of CDH12 and CHD19.
    细胞定位
    Cytoplasm. Nucleus
    UniPort
    参考文献
    参考文献
    Skalniak, L., et al. FEBS J. 276(20):5892-5905(2009)
    Vrotsos, E.G., et al. Brain Res. Bull. 79(2):97-103(2009)
    Niu, J., et al. J. Biol. Chem. 283(21):14542-14551(2008)
    Liang, J., et al. J. Biol. Chem. 283(10):6337-6346(2008)
    Zhou, L., et al. Circ. Res. 98(9):1177-1185(2006)
    ZC12A Antibody (Center) (Cat. #abs100885) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ZC12A antibody detected the ZC12A protein (arrow).
    ZC12A antibody (Center) (Cat. #abs100885) immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ZC12A antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
    ZC12A Antibody (Center) (Cat. #abs100885) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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