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  • Rabbit anti-ZBTB33 Polyclonal Antibody
  • Kaiso; Kaiso protein; Kaiso transcription factor; KAISO_HUMAN; Transcriptional regulator Kaiso; ZBTB 33; Zbtb33; Zinc finger and BTB domain containing 33; Zinc finger and BTB domain-containing protein 33; Zinc finger transcription factor Kaiso; ZNF 348; ZNF Kaiso; ZNF348;
  • 货号: abs132802
    产品说明书
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    货号-规格 货期 价格 数量
    abs132802-50ug 1-2周 ¥1100.00
    - +
    abs132802-100ug 1-2周 ¥1650.00
    - +
    大包装询价
    概述
    别名
    Kaiso; Kaiso protein; Kaiso transcription factor; KAISO_HUMAN; Transcriptional regulator Kaiso; ZBTB 33; Zbtb33; Zinc finger and BTB domain containing 33; Zinc finger and BTB domain-containing protein 33; Zinc finger transcription factor Kaiso; ZNF 348; ZNF Kaiso; ZNF348;
    宿主
    Rabbit
    特异性
    ZBTB33 antibody detects endogenous levels of total ZBTB33.
    反应种属
    Human;Mouse
    应用
    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
    免疫原
    A synthesized peptide.
    性能
    浓度
    1mg/ml
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin .
    类型
    Polyclonal Antibody
    储存/保存方法
    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
    存储溶液
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
    靶标
    背景说明
    Transcriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS). Recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. May contribute to the repression of target genes of the Wnt signaling pathway. May also activate transcription of a subset of target genes by the recruitment of CTNND2. Represses expression of MMP7 in conjunction with transcriptional corepressors CBFA2T3, CBFA2T2 and RUNX1T1 (PubMed:23251453).
    组织特异性
    Expressed in vascular endothelium.
    细胞定位
    Cytosol;Nucleus;Plasma Membrane;
    UniPort
    Western blot analysis of ZBTB33 expression in NIH3T3 whole cell lysate ;,The lane on the left is treated with the antigen-specific peptide.
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