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  • Rabbit anti-ZAP70 Polyclonal Antibody
  • ADMIO2;IMD48;SRK;STCD;STD;TZK;ZAP-70;SRK;STCD;STD;TZK;ZAP-70
  • 货号: abs116057
    产品说明书
    分享:
    货号-规格 货期 价格 数量
    abs116057-50ul 1-2周 ¥1250.00
    - +
    大包装询价
    概述
    别名
    ADMIO2;IMD48;SRK;STCD;STD;TZK;ZAP-70;SRK;STCD;STD;TZK;ZAP-70
    宿主
    Rabbit
    反应种属
    Human,Mouse,Rat
    应用
    WB 1:500 - 1:2000
    IHC 1:50 - 1:200
    IF 1:50 - 1:200
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ZAP70 (NP_001070.2).
    阳性对照
    SW480,U251,Mouse brain,Mouse spleen
    性能
    纯化方法
    Affinity purification
    类型
    Polyclonal Antibody
    同种型
    IgG
    储存/保存方法
    Store at -20℃. Avoid freeze / thaw cycles.
    存储溶液
    Store at -20℃. Avoid freeze / thaw cycles.
    Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
    靶标
    背景说明
    This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.
    细胞定位
    Cell membrane,Cytoplasm,Peripheral membrane protein
    UniPort
    Western blot analysis of extracts of various cell lines, using ZAP70 antibody (abs116057) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.
    Immunohistochemistry of paraffin-embedded human amygdalitis using ZAP70 antibody at dilution of 1:100 (40x lens).
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