Rabbit anti-XPC Polyclonal Antibody
- XPC抗体,p125; RAD4; XP3; XPCC
货号: abs118431
货号-规格 | 货期 | 价格 | 数量 |
abs118431-50ul | 1-2周 | ¥1500.00 | - + |

概述 | ||
别名 | XPC抗体;p125; RAD4; XP3; XPCC | |
宿主 | Rabbit | |
反应种属 | Human | |
应用 | WB 1:500 - 1:2000 IHC 1:50 - 1:100 | |
分子量 | Detects a band of approximately 130kD Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. | |
免疫原 | Recombinant fusion protein containing a sequence corresponding to amino acids 700-940 of human XPC (NP_004619.3). | |
阳性对照 | LO2,HeLa,293T,HT-1080,Jurkat | |
性能 | ||
纯化方法 | Affinity purification | |
类型 | Polyclonal Antibody | |
同种型 | IgG | |
储存/保存方法 | Store at -20℃. Avoid freeze / thaw cycles. | |
存储溶液 | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. | |
靶标 | ||
背景说明 | This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. | |
细胞定位 | Cytoplasm,Nucleus | |
UniProt | ||
Western blot analysis of extracts of various cell lines, using XPC antibody (abs118431) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit . Exposure time: 5s. | ||
Immunohistochemistry of paraffin-embedded human liver cancer using XPC antibody at dilution of 1:100 (40x lens). | ||
温馨提示:本产品仅作科研实验使用,不支持临床等研究 |
- 实验方法 实验条件
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