Rabbit anti-UVRAG Polyclonal Antibody
- UVRAG抗体,DHTX,p63,VPS38
货号: abs118508
货号-规格 | 货期 | 价格 | 数量 |
abs118508-50ul | 1-2周 | ¥1500.00 | - + |

概述 | ||
别名 | UVRAG抗体;DHTX,p63,VPS38 | |
宿主 | Rabbit | |
反应种属 | Human;Mouse;Rat | |
应用 | WB 1:500 - 1:2000 IHC 1:50 - 1:100 | |
分子量 | Detects a band of approximately 100kD (Predicted molecular weight: 35kD/78kD) Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. | |
免疫原 | Recombinant fusion protein containing a sequence corresponding to amino acids 501-699 of human UVRAG (NP_003360.2). | |
阳性对照 | LO2,HeLa,Mouse liver,Rat liver,Rat brain | |
性能 | ||
纯化方法 | Affinity purification | |
类型 | Polyclonal Antibody | |
同种型 | IgG | |
储存/保存方法 | Store at -20℃. Avoid freeze / thaw cycles. | |
存储溶液 | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. | |
靶标 | ||
背景说明 | This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. | |
细胞定位 | Chromosome,Early endosome,Endoplasmic reticulum,Late endosome,Lysosome,Midbody,centromere | |
UniProt | ||
Western blot analysis of extracts of various cell lines, using UVRAG antibody (abs118508) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit . Exposure time: 60s. | ||
Immunohistochemistry of paraffin-embedded human liver injury using UVRAG antibody at dilution of 1:100 (40x lens). | ||
Immunohistochemistry of paraffin-embedded rat lung using UVRAG antibody at dilution of 1:100 (40x lens). | ||
Immunohistochemistry of paraffin-embedded mouse lung using UVRAG antibody at dilution of 1:100 (40x lens). | ||
温馨提示:本产品仅作科研实验使用,不支持临床等研究 |
- 实验方法 实验条件
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