Rabbit anti-UVRAG Polyclonal Antibody

UVRAG抗体;DHTX,p63,VPS38

Rabbit

Human;Mouse;Rat

WB 1:500 - 1:2000
IHC 1:50 - 1:100

Detects a band of approximately 100kD (Predicted molecular weight: 35kD/78kD)
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Recombinant fusion protein containing a sequence corresponding to amino acids 501-699 of human UVRAG (NP_003360.2).

LO2,HeLa,Mouse liver,Rat liver,Rat brain

Affinity purification

Polyclonal Antibody

IgG

Store at -20℃. Avoid freeze / thaw cycles.

Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.

Chromosome,Early endosome,Endoplasmic reticulum,Late endosome,Lysosome,Midbody,centromere