Rabbit anti-TRI18 Polyclonal Antibody

TRI18抗体;BBBG 1; BBBG1; E3 ubiquitin-protein ligase Midline-1; Finger on X and Y mouse homolog of; FXY; GBBB 1; GBBB1; MID 1; Mid1; Midin; Midline 1 (Opitz/BBB syndrome); Midline 1; Midline 1 ring finger; Midline 1 RING finger protein; Midline-1; Midline1; OGS 1; OGS1; OS; OSX; Putative transcription factor XPRF; RING finger protein 59; RING finger protein Midline-1; RNF 59; RNF59; TRI18; TRI18_HUMAN; TRIM 18; TRIM18; Tripartite motif containing protein 18; Tripartite motif protein TRIM18; Tripartite motif-containing protein 18; XPRF; zinc finger on X and Y; mouse; homolog of; Zinc finger X and Y; ZNFXY

Rabbit

TRI18 Antibody detects endogenous levels of total TRI18.

Human, Mouse, Rat

WB 1:1000-3000, IHC 1:200, IF/ICC 1:200-1:500, ELISA(peptide) 1:20000-1:40000

Predicted molecular weight: 75kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

A synthesized peptide derived from Human MID1(Accession O15344), corresponding to amino acid residues P94-C119.

1mg/ml

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin .

Polyclonal Antibody

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.

Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination.

In the fetus, highest expression found in kidney, followed by brain and lung. Expressed at low levels in fetal liver. In the adult, most abundant in heart, placenta and brain.

Phosphorylated on serine and threonine residues.

Cytoskeleton;Cytosol;