Rabbit anti-PHLPP1 Polyclonal Antibody

PHLPP1抗体;PHLPP,PLEKHE1,PPM3A,SCOP

Rabbit

Human;Mouse;Rat

WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200

Detects a band of approximately 185kD (Predicted molecular weight: 133kD/184kD)
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Recombinant fusion protein containing a sequence corresponding to amino acids 1508-1717 of human PHLPP1 (NP_919431.2).

A-375,HeLa,BT-474,Mouse brain,Mouse testis

Affinity purification

Polyclonal Antibody

IgG

Store at -20℃. Avoid freeze / thaw cycles.

Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling.

Cell membrane,Cytoplasm,Membrane,Nucleus,Peripheral membrane protein