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  • Rabbit anti-PCDHA12 Polyclonal Antibody

    促销商品
    • PCDHA12抗体,PCDH-ALPHA12
    货号: abs118533
    产品说明书
    分享:
    货号-规格 货期 价格 数量
    abs118533-50ul 1-2周 ¥1500.00 ¥1050.00
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    大包装询价
    概述
    别名
    PCDHA12抗体;PCDH-ALPHA12
    宿主
    Rabbit
    反应种属
    Human;Mouse;Rat
    应用
    WB 1:500 - 1:2000
    IHC 1:50 - 1:100
    分子量
    Detects a band of approximately 102kD (Predicted molecular weight: 85kD/101kD)
    Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 713-792 of human PCDHA12 (NP_114070.1).
    阳性对照
    HL-60,H460,NIH/3T3,Mouse spinal cord,Mouse brain,Mouse lung,Rat spinal cord,Rat brain
    性能
    纯化方法
    Affinity purification
    类型
    Polyclonal Antibody
    同种型
    IgG
    储存/保存方法
    Store at -20℃. Avoid freeze / thaw cycles.
    存储溶液
    Store at -20℃. Avoid freeze / thaw cycles.
    Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
    靶标
    背景说明
    This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
    细胞定位
    Cell membrane,Single-pass type I membrane protein
    UniProt
    Western blot analysis of extracts of various cell lines, using PCDHA12 antibody (abs118533) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit . Exposure time: 90s.
    Immunohistochemistry of paraffin-embedded human stomach using PCDHA12 antibody at dilution of 1:100 (40x lens).
    Immunohistochemistry of paraffin-embedded human trachea using PCDHA12 antibody at dilution of 1:100 (40x lens).
    温馨提示:本产品仅作科研实验使用,不支持临床等研究
    • 实验方法 实验条件
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