Rabbit anti-MTMR2 Polyclonal Antibody

MTMR2抗体;CMT4B,CMT4B1

Rabbit

Human;Mouse;Rat

WB 1:500 - 1:2000

Detects a band of approximately 65-73kD (Predicted molecular weight: 65kD/73kD)

Recombinant fusion protein containing a sequence corresponding to amino acids 404-643 of human MTMR2 (NP_057240.3).

HeLa,Jurkat,U-87MG,Mouse brain,Mouse kidney,Mouse liver,Rat liver

Affinity purification

Polyclonal Antibody

IgG

Store at -20℃. Avoid freeze / thaw cycles.

Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

This gene is a member of the myotubularin family of phosphoinositide lipid phosphatases. The encoded protein possesses phosphatase activity towards phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive demyelinating neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been found for this gene.

Cytoplasm,Early endosome membrane,Peripheral membrane protein