Rabbit anti-MSH4 Polyclonal Antibody

MSH4抗体

Rabbit

Human,Mouse,Rat

WB 1:500 - 1:2000
IF 1:50 - 1:200

Detects a band of approximately 105kD (Predicted molecular weight: 104kD)
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Recombinant fusion protein containing a sequence corresponding to amino acids 697-936 of human MSH4 (NP_002431.2).

Mouse skeletal muscle,Rat skeletal muscle

Affinity purification

Polyclonal Antibody

IgG

Store at -20℃. Avoid freeze / thaw cycles.

Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair.