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  • Rabbit anti-MSH4 Polyclonal Antibody

    • MSH4抗体
    货号: abs118566
    产品说明书
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    货号-规格 货期 价格 数量
    abs118566-50ul 1-2周 ¥1500.00
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    大包装询价
    概述
    别名
    MSH4抗体
    宿主
    Rabbit
    反应种属
    Human,Mouse,Rat
    应用
    WB 1:500 - 1:2000
    IF 1:50 - 1:200
    分子量
    Detects a band of approximately 105kD (Predicted molecular weight: 104kD)
    Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 697-936 of human MSH4 (NP_002431.2).
    阳性对照
    Mouse skeletal muscle,Rat skeletal muscle
    性能
    纯化方法
    Affinity purification
    类型
    Polyclonal Antibody
    同种型
    IgG
    储存/保存方法
    Store at -20℃. Avoid freeze / thaw cycles.
    存储溶液
    Store at -20℃. Avoid freeze / thaw cycles.
    Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
    靶标
    背景说明
    This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair.
    UniProt
    Western blot analysis of extracts of various cell lines, using MSH4 antibody (abs118566) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit . Exposure time: 90s.
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    • 实验方法 实验条件
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