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  • Rabbit anti-GRPR Polyclonal Antibody

    • GRPR抗体;BB2, Bombesin BB2 receptor, bombesin receptor 2, Gastrin Releasing Peptide Receptor, Gastrin-releasing peptide receptor, GRP preferring bombesin receptor, GRP R, GRP-preferring bombesin receptor, GRP-R, Grp/bombesin receptor, Grpr, GRPR_HUMAN,
    货号: abs133194
    产品说明书
    分享:
    货号-规格 货期 价格 数量
    abs133194-50ug 1-2周 ¥1500.00
    - +
    abs133194-100ug 1-2周 ¥2300.00
    - +
    大包装询价
    概述
    描述
    Receptor for gastrin releasing peptide (GRP). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
    别名
    GRPR抗体;BB2, Bombesin BB2 receptor, bombesin receptor 2, Gastrin Releasing Peptide Receptor, Gastrin-releasing peptide receptor, GRP preferring bombesin receptor, GRP R, GRP-preferring bombesin receptor, GRP-R, Grp/bombesin receptor, Grpr, GRPR_HUMAN,
    宿主
    Rabbit
    特异性
    GRPR antibody detects endogenous levels of total GRPR.
    反应种属
    Human;Mouse;Rat
    预测反应种属
    Pig;Rabbit;Sheep;Dog;Bovine;Horse;
    应用
    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
    分子量
    Predicted molecular weight: 43kD
    免疫原
    A synthesized peptide derived from Human GRPR(Accession P30550), corresponding to amino acid residues S188-S214.
    性能
    浓度
    1mg/ml
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin .
    类型
    Polyclonal Antibody
    储存/保存方法
    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
    存储溶液
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
    靶标
    背景说明
    Receptor for gastrin-releasing peptide (GRP) (PubMed:1655761). Signals via association with G proteins that activate a phosphatidylinositol-calcium second messenger system, resulting in Akt phosphorylation. Contributes to the regulation of food intake. Contributes to the perception of prurient stimuli and transmission of itch signals in the spinal cord that promote scratching behavior, but does not play a role in the perception of pain. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory (By similarity).
    组织特异性
    Highly expressed in pancreas. Also expressed in stomach, adrenal cortex and brain.
    细胞定位
    Plasma Membrane;
    UniProt
    温馨提示:本产品仅作科研实验使用,不支持临床等研究
    • 实验方法 实验条件
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