Rabbit anti-GRPR Polyclonal Antibody

Receptor for gastrin releasing peptide (GRP). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

GRPR抗体;BB2, Bombesin BB2 receptor, bombesin receptor 2, Gastrin Releasing Peptide Receptor, Gastrin-releasing peptide receptor, GRP preferring bombesin receptor, GRP R, GRP-preferring bombesin receptor, GRP-R, Grp/bombesin receptor, Grpr, GRPR_HUMAN,

Rabbit

GRPR antibody detects endogenous levels of total GRPR.

Human;Mouse;Rat

Pig;Rabbit;Sheep;Dog;Bovine;Horse;

WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Predicted molecular weight: 43kD

A synthesized peptide derived from Human GRPR(Accession P30550), corresponding to amino acid residues S188-S214.

1mg/ml

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin .

Polyclonal Antibody

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Receptor for gastrin-releasing peptide (GRP) (PubMed:1655761). Signals via association with G proteins that activate a phosphatidylinositol-calcium second messenger system, resulting in Akt phosphorylation. Contributes to the regulation of food intake. Contributes to the perception of prurient stimuli and transmission of itch signals in the spinal cord that promote scratching behavior, but does not play a role in the perception of pain. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory (By similarity).

Highly expressed in pancreas. Also expressed in stomach, adrenal cortex and brain.

Plasma Membrane;