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  • Rabbit anti-GPR44 Polyclonal Antibody

    • GPR44抗体,CD294, CD294 antigen, Chemoattractant receptor homologous molecule expressed on Th2 cells, chemoattractant receptor-homologous, Chemoattractant receptor-homologous molecule expressed on Th2 cells, CRTH 2, CRTH2, DL1R, DP2 prostaglandin receptor, G Protein Coupled Receptor 44, GPR 44, Gpr44, GPR44_HUMAN, PTGDR2, Putative G protein coupled receptor 44, Putative G-protein coupled receptor 44,
    货号: abs133186
    产品说明书
    分享:
    货号-规格 货期 价格 数量
    abs133186-50ug 1-2周 ¥1500.00
    - +
    abs133186-100ug 1-2周 ¥2300.00
    - +
    大包装询价
    概述
    描述
    Orphan receptor;
    别名
    GPR44抗体;CD294, CD294 antigen, Chemoattractant receptor homologous molecule expressed on Th2 cells, chemoattractant receptor-homologous, Chemoattractant receptor-homologous molecule expressed on Th2 cells, CRTH 2, CRTH2, DL1R, DP2 prostaglandin receptor, G Protein Coupled Receptor 44, GPR 44, Gpr44, GPR44_HUMAN, PTGDR2, Putative G protein coupled receptor 44, Putative G-protein coupled receptor 44,
    宿主
    Rabbit
    特异性
    GPR44 antibody detects endogenous levels of total GPR44.
    反应种属
    Human;Mouse
    应用
    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
    分子量
    Predicted molecular weight: 43kD
    Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
    免疫原
    A synthesized peptide derived from Human PTGDR2(Accession Q9Y5Y4), corresponding to amino acid residues M181-L206.
    性能
    浓度
    1mg/ml
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin .
    类型
    Polyclonal Antibody
    储存/保存方法
    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
    存储溶液
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
    靶标
    背景说明
    Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca2+ mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.
    组织特异性
    Widespread expression. High expression in stomach, small intestine, heart and thymus. Intermediate expression in colon, spinal cord and peripheral blood and low expression in brain, skeletal muscle and spleen. Expressed also on Th2- and Tc2- type cells, eosinophils and basophils.
    翻译后修饰
    Phosphorylated.
    细胞定位
    Plasma Membrane;
    UniProt
    温馨提示:本产品仅作科研实验使用,不支持临床等研究
    • 实验方法 实验条件
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