Rabbit anti-GPHN Polyclonal Antibody

GPHN抗体;GEPH,GPH,GPHRYN,HKPX1,MOCODC

Rabbit

Human;Mouse;Rat

WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200

Detects a band of approximately 103kD (Predicted molecular weight: 79kD/83kD)
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Recombinant fusion protein containing a sequence corresponding to amino acids 520-769 of human GPHN (NP_065857.1).

293T,Mouse brain,Mouse liver,Rat brain

Affinity purification

Polyclonal Antibody

IgG

Store at -20℃. Avoid freeze / thaw cycles.

Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known.

Cell junction,Cytoplasm,Cytoplasmic side,Peripheral membrane protein,cytoskeleton,postsynaptic cell membrane,synapse