Rabbit anti-GAS41 Polyclonal Antibody

GAS41抗体;4930573H17Rik, B230215M10Rik, GAS 41, Gas41, glioma amplified sequence 41, Glioma-amplified sequence 41, glioma-amplified sequence-41, gliomaamplified sequence 41, gliomaamplified sequence41, NUBI 1, NuBI-1, NuBI1, NuMA binding protein 1, NuMA-binding protein 1, YAF9, YEATS domain containing 4, YEATS domain containing4, YEATS domain-containing protein 4, YEATS4, YETS4_HUMAN,

Rabbit

GAS41 Antibody detects endogenous levels of total GAS41.

Human;Mouse

WB 1:500~1:1000, ELISA(peptide) 1:20000-1:40000

Predicted molecular weight: 40KD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

A synthesized peptide derived from Human YEATS4(Accession O95619), corresponding to amino acid residues N76-I98.

1mg/ml

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin .

Polyclonal Antibody

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.

Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.

Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle.

Nucleus;