Rabbit anti-FADS2 Polyclonal Antibody

FADS2抗体;D6D,DES6,FADSD6,LLCDL2,SLL0262,TU13

Rabbit

Human;Mouse

WB 1:500 - 1:2000

Detects a band of approximately 52kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Recombinant fusion protein containing a sequence corresponding to amino acids 1-131 of human FADS2 (NP_004256.1).

HepG2,A-549,U-87MG,HeLa,Mouse liver,Mouse brain

Affinity purification

IgG

Store at -20℃. Avoid freeze / thaw cycles.

Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. Alternative splicing results in multiple transcript variants encoding different isoforms.

Endoplasmic reticulum membrane,Multi-pass membrane protein