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  • Rabbit anti-EZH1 Polyclonal Antibody

    • EZH1抗体,Enhancer of zeste homolog 1 (Drosophila), Enhancer of zeste homolog 1, ENX-2, ENX2, Ezh1, EZH1_HUMAN, Histone-lysine N-methyltransferase EZH1,
    货号: abs133683
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    货号-规格 货期 价格 数量
    abs133683-50ug 1-2周 ¥1500.00
    - +
    abs133683-100ug 1-2周 ¥2300.00
    - +
    大包装询价
    概述
    别名
    EZH1抗体;Enhancer of zeste homolog 1 (Drosophila), Enhancer of zeste homolog 1, ENX-2, ENX2, Ezh1, EZH1_HUMAN, Histone-lysine N-methyltransferase EZH1,
    宿主
    Rabbit
    特异性
    EZH1 Antibody detects endogenous levels of total EZH1.
    反应种属
    Human;Mouse
    应用
    WB 1:500~1:1000, IHC: 1:50~1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    分子量
    Predicted molecular weight: 85kD
    Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
    免疫原
    A synthesized peptide derived from Human EZH1(Accession Q92800), corresponding to amino acid residues Q185-K206.
    性能
    浓度
    1mg/ml
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin .
    类型
    Polyclonal Antibody
    储存/保存方法
    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
    存储溶液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
    靶标
    背景说明
    Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.
    细胞定位
    Nucleus;
    UniProt
    温馨提示:本产品仅作科研实验使用,不支持临床等研究
    • 实验方法 实验条件
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