Rabbit anti-EZH1 Polyclonal Antibody
- EZH1抗体,Enhancer of zeste homolog 1 (Drosophila), Enhancer of zeste homolog 1, ENX-2, ENX2, Ezh1, EZH1_HUMAN, Histone-lysine N-methyltransferase EZH1,
货号: abs133683
货号-规格 | 货期 | 价格 | 数量 |
abs133683-50ug | 1-2周 | ¥1500.00 | - + |
abs133683-100ug | 1-2周 | ¥2300.00 | - + |

概述 | |
别名 | EZH1抗体;Enhancer of zeste homolog 1 (Drosophila), Enhancer of zeste homolog 1, ENX-2, ENX2, Ezh1, EZH1_HUMAN, Histone-lysine N-methyltransferase EZH1, |
宿主 | Rabbit |
特异性 | EZH1 Antibody detects endogenous levels of total EZH1. |
反应种属 | Human;Mouse |
应用 | WB 1:500~1:1000, IHC: 1:50~1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000 |
分子量 | Predicted molecular weight: 85kD Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
免疫原 | A synthesized peptide derived from Human EZH1(Accession Q92800), corresponding to amino acid residues Q185-K206. |
性能 | |
浓度 | 1mg/ml |
纯化方法 | The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin . |
类型 | Polyclonal Antibody |
储存/保存方法 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles |
存储溶液 | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt. |
靶标 | |
背景说明 | Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. |
细胞定位 | Nucleus; |
UniProt | |
温馨提示:本产品仅作科研实验使用,不支持临床等研究 |
- 实验方法 实验条件
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