Rabbit anti-EXOSC1 Polyclonal Antibody

EXOSC1抗体;CGI-108,CSL4,Csl4p,p13,SKI4,Ski4p

Rabbit

Human

WB 1:500 - 1:2000

Detects a band of approximately 21kD (Predicted molecular weight: 21kD)
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Recombinant fusion protein containing a sequence corresponding to amino acids 1-195 of human EXOSC1 (NP_057130.1).

HeLa,U-87MG,MCF-7

Affinity purification

IgG

Store at -20℃. Avoid freeze / thaw cycles.

Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. Alternative splicing of this gene results in multiple transcript variants.

Cytoplasm,Nucleus,nucleolus