Rabbit anti-EIF2B3 Polyclonal Antibody

EIF2B3抗体;EIF-2B,EIF2Bgamma

Rabbit

Human;Mouse;Rat

WB 1:1000 - 1:2000
IHC 1:50 - 1:200

Detects a band of approximately 50kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human EIF2B3 (NP_065098.1).

HepG2,K-562,HT-29,Mouse heart,Mouse lung,Mouse brain,Rat liver

Affinity purification

IgG

Store at -20℃. Avoid freeze / thaw cycles.

Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.