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  • Rabbit anti-EHMT1 Polyclonal Antibody

    • EHMT1抗体,bA188C12.1,Eu-HMTase1,EUHMTASE1,FP13812,GLP,GLP1,KMT1D
    货号: abs118542
    产品说明书
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    货号-规格 货期 价格 数量
    abs118542-50ul 1-2周 ¥1500.00
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    大包装询价
    概述
    别名
    EHMT1抗体;bA188C12.1,Eu-HMTase1,EUHMTASE1,FP13812,GLP,GLP1,KMT1D
    宿主
    Rabbit
    反应种属
    Human;Mouse;Rat
    应用
    WB 1:500 - 1:2000
    分子量
    Detects a band of approximately 141kD
    Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human EHMT1 (NP_079033.4).
    阳性对照
    Raji,293T,HepG2,BT-474,Mouse brain,Rat brain
    性能
    纯化方法
    Affinity purification
    类型
    Polyclonal Antibody
    同种型
    IgG
    储存/保存方法
    Store at -20℃. Avoid freeze / thaw cycles.
    存储溶液
    Store at -20℃. Avoid freeze / thaw cycles.
    Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
    靶标
    背景说明
    The protein encoded by this gene is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. The encoded protein methylates the Lys-9 position of histone H3, which tags it for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants.
    细胞定位
    Chromosome,Nucleus
    UniProt
    Western blot analysis of extracts of various cell lines, using EHMT1 antibody (abs118542) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit . Exposure time: 3s.
    温馨提示:本产品仅作科研实验使用,不支持临床等研究
    • 实验方法 实验条件
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