Rabbit anti-EDG8 Polyclonal Antibody

Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.;

EDG8抗体;EDG 8, EDG8 S1P receptor, Endothelial differentiation G protein coupled receptor 8, Endothelial differentiation G-protein-coupled receptor 8, Endothelial Differentiation Gene 8, Endothelial differentiation sphingolipid G protein coupled receptor 8, S1P receptor 5, S1P receptor Edg 8, S1P receptor Edg-8, S1P receptor Edg8, S1P5, S1PR5, S1PR5_HUMAN, Sphingosine 1 Phosphate Receptor 5, Sphingosine 1 phosphate receptor Edg 8, Sphingosine 1 phosphate receptor Edg8, Sphingosine 1-phosphate receptor 5, Sphingosine 1-phosphate receptor Edg-8, SPPR 1, SPPR 2, SPPR1, SPPR2,

Rabbit

EDG8 antibody detects endogenous levels of total EDG8.

Human;Mouse;Rat

WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Predicted molecular weight: 42kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

A synthesized peptide derived from Human S1PR5(Accession Q9H228), corresponding to amino acid residues P353-S376.

1mg/ml

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin .

Polyclonal Antibody

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.

Widely expressed in the brain, most prominently in the corpus callosum, which is predominantly white matter. Detected in spleen, peripheral blood leukocytes, placenta, lung, aorta and fetal spleen. Low-level signal detected in many tissue extracts. Overexpressed in leukemic large granular lymphocytes. Isoform 1 is predominantly expressed in peripheral tissues. Isoform 2 is expressed in brain, spleen and peripheral blood leukocytes.

Plasma Membrane;