Rabbit anti-EDG8 Polyclonal Antibody
- EDG8抗体,EDG 8, EDG8 S1P receptor, Endothelial differentiation G protein coupled receptor 8, Endothelial differentiation G-protein-coupled receptor 8, Endothelial Differentiation Gene 8, Endothelial differentiation sphingolipid G protein coupled receptor 8, S1P receptor 5, S1P receptor Edg 8, S1P receptor Edg-8, S1P receptor Edg8, S1P5, S1PR5, S1PR5_HUMAN, Sphingosine 1 Phosphate Receptor 5, Sphingosine 1 phosphate receptor Edg 8, Sphingosine 1 phosphate receptor Edg8, Sphingosine 1-phosphate receptor 5, Sphingosine 1-phosphate receptor Edg-8, SPPR 1, SPPR 2, SPPR1, SPPR2,
货号: abs133166
货号-规格 | 货期 | 价格 | 数量 |
abs133166-50ug | 1-2周 | ¥1500.00 | - + |
abs133166-100ug | 1-2周 | ¥2300.00 | - + |

概述 | |
描述 | Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.; |
别名 | EDG8抗体;EDG 8, EDG8 S1P receptor, Endothelial differentiation G protein coupled receptor 8, Endothelial differentiation G-protein-coupled receptor 8, Endothelial Differentiation Gene 8, Endothelial differentiation sphingolipid G protein coupled receptor 8, S1P receptor 5, S1P receptor Edg 8, S1P receptor Edg-8, S1P receptor Edg8, S1P5, S1PR5, S1PR5_HUMAN, Sphingosine 1 Phosphate Receptor 5, Sphingosine 1 phosphate receptor Edg 8, Sphingosine 1 phosphate receptor Edg8, Sphingosine 1-phosphate receptor 5, Sphingosine 1-phosphate receptor Edg-8, SPPR 1, SPPR 2, SPPR1, SPPR2, |
宿主 | Rabbit |
特异性 | EDG8 antibody detects endogenous levels of total EDG8. |
反应种属 | Human;Mouse;Rat |
应用 | WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000 |
分子量 | Predicted molecular weight: 42kD Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
免疫原 | A synthesized peptide derived from Human S1PR5(Accession Q9H228), corresponding to amino acid residues P353-S376. |
性能 | |
浓度 | 1mg/ml |
纯化方法 | The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin . |
类型 | Polyclonal Antibody |
储存/保存方法 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles |
存储溶液 | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
靶标 | |
背景说明 | Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells. |
组织特异性 | Widely expressed in the brain, most prominently in the corpus callosum, which is predominantly white matter. Detected in spleen, peripheral blood leukocytes, placenta, lung, aorta and fetal spleen. Low-level signal detected in many tissue extracts. Overexpressed in leukemic large granular lymphocytes. Isoform 1 is predominantly expressed in peripheral tissues. Isoform 2 is expressed in brain, spleen and peripheral blood leukocytes. |
细胞定位 | Plasma Membrane; |
UniProt | |
温馨提示:本产品仅作科研实验使用,不支持临床等研究 |
- 实验方法 实验条件
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