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  • Rabbit anti-DYR1B Polyclonal Antibody

    • DYR1B抗体,AOMS3, Dual specificity tyrosine (Y) phosphorylation regulated kinase 1B, Dual specificity tyrosine phosphorylation regulated kinase 1B, Dual specificity tyrosine-phosphorylation-regulated kinase 1B, DYR 1B, DYR1A, DYR1B, DYR1B_HUMAN, DYRK 1B, Dyrk1b, Minibrain related kinase, Minibrain-related kinase, MIRK, Mirk protein kinase,
    货号: abs133786
    产品说明书
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    货号-规格 货期 价格 数量
    abs133786-50ug 1-2周 ¥1500.00
    - +
    abs133786-100ug 1-2周 ¥2300.00
    - +
    大包装询价
    概述
    别名
    DYR1B抗体;AOMS3, Dual specificity tyrosine (Y) phosphorylation regulated kinase 1B, Dual specificity tyrosine phosphorylation regulated kinase 1B, Dual specificity tyrosine-phosphorylation-regulated kinase 1B, DYR 1B, DYR1A, DYR1B, DYR1B_HUMAN, DYRK 1B, Dyrk1b, Minibrain related kinase, Minibrain-related kinase, MIRK, Mirk protein kinase,
    宿主
    Rabbit
    特异性
    DYR1B Antibody detects endogenous levels of total DYR1B.
    反应种属
    Human;Mouse
    预测反应种属
    Rabbit;Pig;Dog;Bovine;
    应用
    WB 1:500~1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    分子量
    Predicted molecular weight: 70KD
    Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
    免疫原
    A synthesized peptide derived from Human DYRK1B(Accession Q9Y463), corresponding to amino acid residues Y346-R374.
    性能
    浓度
    1mg/ml
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin .
    类型
    Polyclonal Antibody
    储存/保存方法
    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
    存储溶液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
    靶标
    背景说明
    Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase (G6PC).
    组织特异性
    Highest expression in skeletal muscle, testis, heart and brain with little expression in colon or lung. Expressed in a variety of tumor cell lines.
    翻译后修饰
    Autophosphorylated on tyrosine residues. Phosphorylated by MAP kinase. Tyrosine phosphorylation may be required for dimerization.
    细胞定位
    Nucleus;
    UniProt
    温馨提示:本产品仅作科研实验使用,不支持临床等研究
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