Rabbit anti-DYR1B Polyclonal Antibody
- DYR1B抗体,AOMS3, Dual specificity tyrosine (Y) phosphorylation regulated kinase 1B, Dual specificity tyrosine phosphorylation regulated kinase 1B, Dual specificity tyrosine-phosphorylation-regulated kinase 1B, DYR 1B, DYR1A, DYR1B, DYR1B_HUMAN, DYRK 1B, Dyrk1b, Minibrain related kinase, Minibrain-related kinase, MIRK, Mirk protein kinase,
货号: abs133786
货号-规格 | 货期 | 价格 | 数量 |
abs133786-50ug | 1-2周 | ¥1500.00 | - + |
abs133786-100ug | 1-2周 | ¥2300.00 | - + |

概述 | |
别名 | DYR1B抗体;AOMS3, Dual specificity tyrosine (Y) phosphorylation regulated kinase 1B, Dual specificity tyrosine phosphorylation regulated kinase 1B, Dual specificity tyrosine-phosphorylation-regulated kinase 1B, DYR 1B, DYR1A, DYR1B, DYR1B_HUMAN, DYRK 1B, Dyrk1b, Minibrain related kinase, Minibrain-related kinase, MIRK, Mirk protein kinase, |
宿主 | Rabbit |
特异性 | DYR1B Antibody detects endogenous levels of total DYR1B. |
反应种属 | Human;Mouse |
预测反应种属 | Rabbit;Pig;Dog;Bovine; |
应用 | WB 1:500~1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000 |
分子量 | Predicted molecular weight: 70KD Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
免疫原 | A synthesized peptide derived from Human DYRK1B(Accession Q9Y463), corresponding to amino acid residues Y346-R374. |
性能 | |
浓度 | 1mg/ml |
纯化方法 | The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin . |
类型 | Polyclonal Antibody |
储存/保存方法 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles |
存储溶液 | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt. |
靶标 | |
背景说明 | Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase (G6PC). |
组织特异性 | Highest expression in skeletal muscle, testis, heart and brain with little expression in colon or lung. Expressed in a variety of tumor cell lines. |
翻译后修饰 | Autophosphorylated on tyrosine residues. Phosphorylated by MAP kinase. Tyrosine phosphorylation may be required for dimerization. |
细胞定位 | Nucleus; |
UniProt | |
温馨提示:本产品仅作科研实验使用,不支持临床等研究 |
- 实验方法 实验条件
共 0 张,还能上传 8 张 提交
- 提示: 尊敬的客户您好,如果您对我们的产品有什么疑问或想要了解的,可以点击“我要咨询”按钮填写您的疑问。
提交不成功?请联系info@absin.cn。
促销资讯 更多
订购信息
您可以从我们的授权经销商处购买absin产品或获得技术支持。若要查看您所在地区的经销商,请从以下的下拉列表中选择。