Rabbit anti-CSE1L Polyclonal Antibody
- CSE1L抗体,CAS,CSE1,XPO2
货号: abs118644
货号-规格 | 货期 | 价格 | 数量 |
abs118644-50ul | 1-2周 | ¥1500.00 | - + |

概述 | ||
别名 | CSE1L抗体;CAS,CSE1,XPO2 | |
宿主 | Rabbit | |
反应种属 | Human,Rat | |
应用 | WB 1:500 - 1:2000 IHC 1:50 - 1:200 | |
分子量 | Detects a band of approximately 110kD Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. | |
免疫原 | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human CSE1L (NP_001243064.1). | |
阳性对照 | B-cell,U-87MG,LO2,BT-474 | |
性能 | ||
纯化方法 | Affinity purification | |
类型 | Polyclonal Antibody | |
同种型 | IgG | |
储存/保存方法 | Store at -20℃. Avoid freeze / thaw cycles. | |
存储溶液 | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. | |
靶标 | ||
背景说明 | Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. | |
细胞定位 | Cytoplasm,Nucleus | |
UniProt | ||
Western blot analysis of extracts of various cell lines, using CSE1L antibody (abs118644) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit . Exposure time: 5s. | ||
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- 实验方法 实验条件
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