首页 产品中心
  • Rabbit anti-CJ119 (N-term) Polyclonal Antibody
  • Mini-chromosome maintenance complex-binding protein, MCM-BP, MCM-binding protein, MCMBP, C10orf119;MCMBP;C10orf119
  • 货号: abs106763
    产品说明书
    分享:
    货号-规格 货期 价格 数量
    abs106763-50ul 1-2周 ¥1250.00
    - +
    大包装询价
    概述
    描述
    Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
    别名
    Mini-chromosome maintenance complex-binding protein, MCM-BP, MCM-binding protein, MCMBP, C10orf119;MCMBP;C10orf119
    宿主
    Rabbit
    特异性
    This CJ119 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-171 amino acids from the N-terminal region of human CJ119.
    反应种属
    Human
    预测反应种属
    B, M, R
    应用
    WB~~1:1000
    IHC-P~~1:50~100
    FC~~1:10~50
    性能
    类型
    Polyclonal Antibody
    同种型
    Rabbit Ig
    储存/保存方法
    Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
    存储溶液
    Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
    研究领域
    Cell Biology
    靶标
    背景说明
    Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the MCM complex without addition of ATP; probably acts by destabilizing interactions of each individual subunits of the MCM complex. Required for sister chromatid cohesion.
    细胞定位
    Nucleus. Note=Associates with chromatin. Highly associated with chromatin in G1/S and S phases, reduced binding to chromatin in G2, and further decreased binding in early M phase. It then reassociates with chromatin in late M phase. Dissociates from chromatin later than component of the MCM complex
    UniPort
    Q9BTE3
    参考文献
    参考文献
    Takahashi, N., et al. PLoS Genet. 6 (1), E1000817 (2010)
    Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
    Sakwe, A.M., et al. Mol. Cell. Biol. 27(8):3044-3055(2007)
    Western blot analysis of CJ119 Antibody (N-term) (Cat. #abs106763) in MDA-MB231 cell line lysates (35ug/lane). CJ119 (arrow) was detected using the purified Pab.
    CJ119 Antibody (N-term) (Cat. #abs106763) immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix carcinoma tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CJ119 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    CJ119 Antibody (N-term) (Cat. #abs106763) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
    温馨提示:本产品仅作科研实验使用,不支持临床等研究
        提示: 尊敬的客户您好,如果您对我们的产品有什么疑问或想要了解的,可以点击“我要提问”按钮填写您的疑问。
        提交不成功?请联系info@absin.cn。
        我要提问

    促销资讯 更多

      订购信息
      您可以从我们的授权经销商处购买absin产品或获得技术支持。若要查看您所在地区的经销商,请从以下的下拉列表中选择。
      GO
      • 0