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  • Rabbit anti-CIDEA Polyclonal Antibody
  • Cell death activator CIDE A; Cell Death Inducing DFFA Like Effector A; cell death inducing DNA fragmentation factor, alpha subunit like effector A; CIDE-A; CIDEA;
  • 货号: abs138573
    产品说明书
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    货号-规格 货期 价格 数量
    abs138573-50ug 1-2周 ¥1100.00
    - +
    abs138573-100ug 1-2周 ¥1650.00
    - +
    大包装询价
    概述
    别名
    Cell death activator CIDE A; Cell Death Inducing DFFA Like Effector A; cell death inducing DNA fragmentation factor, alpha subunit like effector A; CIDE-A; CIDEA;
    宿主
    Rabbit
    特异性
    CIDEA Antibody detects endogenous levels of total CIDEA.
    反应种属
    Human
    预测反应种属
    Rabbit;Sheep;Dog;Horse;Bovine
    应用
    WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
    免疫原
    A synthesized peptide derived from human CIDEA.
    性能
    浓度
    1mg/ml
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin .
    类型
    Polyclonal Antibody
    储存/保存方法
    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
    存储溶液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
    靶标
    背景说明
    Acts as a CEBPB coactivator in mammary epithelial cells to control the expression of a subset of CEBPB downstream target genes, including ID2, IGF1, PRLR, SOCS1, SOCS3, XDH, but not casein. By interacting with CEBPB, strengthens the association of CEBPB with the XDH promoter, increases histone acetylation and dissociates HDAC1 from the promoter (By similarity). Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair and occurs at a lower rate than that promoted by CIDEC. When overexpressed, induces apoptosis. The physiological significance of its role in apoptosis is unclear.
    组织特异性
    Expressed in omental and subcutaneous adipose tissue (at protein level).
    细胞定位
    Cytosol;Mitochondrion;Nucleus;
    UniPort
    Western blot analysis CIDEA using COS7 whole cell lysates
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