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  • Rabbit anti-CIDEA Polyclonal Antibody
  • CIDE-A
  • 货号: abs118024
    产品说明书
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    货号-规格 货期 价格 数量
    abs118024-50ul 1-2周 ¥1250.00
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    大包装询价
    概述
    别名
    CIDE-A
    宿主
    Rabbit
    反应种属
    Human
    应用
    IF 1:50 - 1:100
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 20-219 of human CIDEA (NP_001270.1).
    性能
    纯化方法
    Affinity purification
    类型
    Polyclonal Antibody
    同种型
    IgG
    储存/保存方法
    Store at -20℃. Avoid freeze / thaw cycles.
    存储溶液
    Store at -20℃. Avoid freeze / thaw cycles.
    Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
    靶标
    背景说明
    This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.
    细胞定位
    Lipid droplet,Nucleus
    UniPort
    Immunofluorescence analysis of A549 cell using CIDEA antibody. Blue: DAPI for nuclear staining.
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