Rabbit anti-ATF6B Polyclonal Antibody

ATF6B抗体;Activating transcription factor 6 beta, ATF 6 beta, ATF6-beta, ATF6B, ATF6B_HUMAN, ATF6beta, cAMP response element binding protein related protein, cAMP response element-binding protein-related protein, cAMP responsive element binding protein like 1, cAMP-dependent transcription factor ATF-6 beta, cAMP-responsive element-binding protein-like 1, CREB L1, Creb related protein, CREB RP, Creb-rp, CREBL 1, CREBL1, Crebrp, Cyclic AMP dependent transcription factor ATF 6 beta, Cyclic AMP dependent transcription factor ATF6 beta, FLJ10066, G13, G13 protein, OTTHUMP00000029432, OTTHUMP00000029433, Processed cyclic AMP-dependent transcription factor ATF-6 beta, Protein G13,

Rabbit

ATF6B Antibody detects endogenous levels of total ATF6B.

Human;Mouse

WB 1:500~1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Predicted molecular weight: 77kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

A synthesized peptide derived from Human ATF6B(Accession Q99941), corresponding to amino acid residues E418-L439.

1mg/ml

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin .

Polyclonal Antibody

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.

Transcriptional factor that acts in the unfolded protein response (UPR) pathway by activating UPR target genes induced during ER stress. Binds DNA on the 5'-CCAC[GA]-3' half of the ER stress response element (ERSE) (5'-CCAATN9CCAC[GA]-3') when NF-Y is bound to ERSE.

Ubiquitous.

N-glycosylated.During unfolded protein response, a fragment of approximately 60 kDa containing the cytoplasmic transcription factor domain is released by proteolysis. The cleavage is probably performed sequentially by site-1 and site-2 proteases.

Endoplasmic reticulum;Golgi apparatus;Nucleus;