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  • Rabbit Anti-c-Myc tag Polyclonal Antibody
  • avian myelocytomatosis viral oncogene homolog; bHLHe39; c-Myc; C-Myc-Tag; class E basic helix-loop-helix protein 39; MRTL; MYC; Myc Epitope Tag; myc proto-oncogene protein; myc-related translation/localization regulatory factor; oncogene c-Myc; proto-oncogene c-Myc; protooncogene homologous to myelocytomatosis virus; transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog (avian); MYC_HUMAN.  
  • 货号: abs120247
    产品说明书
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    货号-规格 货期 价格 数量
    abs120247-50ul 1-2周 ¥1100.00
    - +
    abs120247-100ul 1-2周 ¥1650.00
    - +
    大包装询价
    概述
    别名
    avian myelocytomatosis viral oncogene homolog;
    bHLHe39;
    c-Myc;
    C-Myc-Tag;
    class E basic helix-loop-helix protein 39;
    MRTL;
    MYC;
    Myc Epitope Tag;
    myc proto-oncogene protein;
    myc-related translation/localization regulatory factor;
    oncogene c-Myc;
    proto-oncogene c-Myc;
    protooncogene homologous to myelocytomatosis virus;
    transcription factor p64;
    v-myc avian myelocytomatosis viral oncogene homolog;
    v-myc myelocytomatosis viral oncogene homolog (avian);
    MYC_HUMAN.  
    宿主
    Rabbit
    特异性
    Myc tag
    反应种属
    All
    应用
    WB=1:100-5000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)
    免疫原
    KLH conjugated C-EQKLISEEDL (human Proto-oncogene c-Myc): 
    性能
    浓度
    1mg/ml
    纯化方法
    affinity purified by Protein A
    类型
    Polyclonal Antibody
    同种型
    IgG
    储存/保存方法
    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
    存储溶液
    0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    研究领域
    肿瘤 免疫学 染色质和核信号 信号转导 细胞周期蛋白 转录调节因子 细胞分化
    靶标
    背景说明
    Epitope tags are useful for the labeling and detection of proteins usingimmunoblotting, immunoprecipitation and immunostaining techniques. Due to their small size, they are unlikely to affect the tagged protein's biochemical properties. The Myc epitope tag is widely used to detect expression of recombinant proteins in bacteria, yeast,insect and mammalian cell systems.

    The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.
    细胞定位
    细胞核 
    UniPort
    Sample:
    K562 Cell (Human) Lysate at 40 ug
    Primary: Anti-Myc tag at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 49 kD
    Observed band size: 45 kD
    Sample:
    Hela Cell (Human) Lysate at 40 ug
    Primary: Anti-Myc tag at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 49 kD
    Observed band size: 45 kD
    温馨提示:本产品仅作科研实验使用,不支持临床等研究
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