Rabbit Anti-ASBT Polyclonal Antibody

ASBT抗体;SLC10A2, Apical sodium dependent bile acid transporter, Apical sodium- dependent bile acid transporter, IBAT, ileal apical sodium-dependent bile acid transporter, Ileal sodium dependent bile acid transporter, Ileal sodium-dependent bile acid transporter, Ileal sodium/bile acid cotransporter, ISBT, Na+ bile acid cotransporter, Na+ dependent ileal bile acid transporter, NTCP2, Sodium/taurocholate cotransporting polypeptide, ileal, solute carrier family 10 (sodium/bile acid cotransporter family), Solute carrier family 10 member 2. , ,

Rabbit

ASBT

Human;Mouse;Rat;Dog;Horse;

ELISA=1:500-1000 

Predicted molecular weight: 38kDa

KLH conjugated synthetic peptide derived from human ASBT:131-230/348 

1mg/ml

affinity purified by Protein A

Polyclonal Antibody

IgG

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

肿瘤  免疫学  信号转导  通道蛋白  

SLC10A2 plays a critical role in reabsorption of bile acids from the the small intestine lumen. Passive flow of sodium ions down their concentration gradient is coupled to bile acid movement, resulting in an increase in the concentration of bile acids in the interior of the cell. This action conserves the body's pool of re-circulating bile acid. SLC10A2 also plays a key role in cholesterol metabolism as cholesterol is the precursor molecule in bile acid synthesis mediated by CYP7A and FXR.

细胞膜