Rabbit anti-ADAM19 Polyclonal Antibody

ADAM19抗体;FKSG34,MADDAM,MLTNB

Rabbit

Human;Mouse;Rat

WB 1:500 - 1:2000
IF 1:50 - 1:200

Detects a band of approximately 72kD (Predicted molecular weight: 100kD/104kD)
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Recombinant fusion protein containing a sequence corresponding to amino acids 203-460 of human ADAM19 (NP_150377.1).

HT-1080,SW480,NIH/3T3,Mouse heart,Mouse lung,Mouse liver,Mouse kidney,Rat heart

Affinity purification

IgG

Store at -20℃. Avoid freeze / thaw cycles.

Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase, which may be involved in normal physiological processes such as cell migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. It is proposed to play a role in pathological processes, such as cancer, inflammatory diseases, renal diseases, and Alzheimer's disease.

Membrane,Single-pass type I membrane protein