PKM2 inhibitor
- PKM2-IN-1;compound 3k
货号: abs814498
货号-规格 | 货期 | 价格 | 数量 |
abs814498-5mg | 现货 | ¥824.00 | - + |
abs814498-25mg | 现货 | ¥3081.00 | - + |

产品描述 | ||
描述 | PKM2 inhibitor(Compound 3K) displays PKM2 inhibitory activity with the IC50 value of 2.95 μM. The IC50 value for PKM1 is 4-5-fold higher than that for PKM2. | |
纯度 | >98% | |
储存/保存方法 | Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution. | |
基本信息 | ||
别名 | PKM2-IN-1;compound 3k | |
外观 | Powder | |
可溶性/溶解性 | DMSO : 6 mg/mL (17.36 mM) | |
生物活性 | ||
靶点 | PKM1,PKM2 | |
In vitro(体外研究) | The well performing compound 3k shows nanomolar antiproliferative activity toward a series of cancer cell lines with high expression of PKM2 including HCT116, Hela and H1299 with IC50 values ranging from 0.18-1.56 μM. Moreover, compound 3k exhibits more cytotoxicity on cancer cells than normal cells. | |
温馨提示:本产品仅作科研实验使用,不支持临床等研究 |
- 实验方法 实验条件
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