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  • OAC2
    • OAC-2,OAC 2
    货号: abs810255
    CAS号: 6019-39-2
    分子式: C15H12N2O
    分子量: 236.27
    产品说明书
    分享:
    货号-规格 货期 价格 数量
    abs810255-5mg 1-2周 ¥573.00
    - +
    abs810255-10mg 1-2周 ¥728.00
    - +
    abs810255-50mg 1-2周 ¥2580.00
    - +
    abs810255-100mg 1-2周 ¥4268.00
    - +
    大包装询价
    产品描述
    描述
    OAC2 is an Oct4-activating compound which activates expression through the Oct4 gene promoter; enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells (iPSCs) from embryonic fibroblasts; an analog of OAC1.
    纯度
    >98%
    储存/保存方法
    store at -20℃ for one year(Powder);
    in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months.
    基本信息
    别名
    OAC-2,OAC 2
    外观
    Powder
    可溶性/溶解性
    DMSO: ≥ 2.4 mg/mL
    生物活性
    靶点
    Oct3_4
    In vitro(体外研究)
    Octamer-binding transcription factor 4 (Oct4) is a master regulator of the induction and maintenance of cellular pluripotency, and has crucial roles in early stages of differentiation. It is the only factor that cannot be substituted by other members of the same protein family to induce pluripotency. Oct4 has been shown to be an essential regulator of embryonic stem cell (ESC) pluripotency and key to the reprogramming process. OAC2 is a structural analog of OAC1. OAC2 activates both Oct4 and Nanog reporters to a similar extent as OAC1. OAC1 and its two structural analogs OAC2 and OAC3 enhances reprogramming efficiency fourfold, up to as high as 2.75%, and accelerates the appearance of iPSC colonies 3 to 4 d when used in combination with the four reprogramming factors, Oct4, Sox2, Klf4, and c-Myc.
    温馨提示:本产品仅作科研实验使用,不支持临床等研究
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